Arash Salardini, MD

Assistant Professor of Neurology

Departments & Organizations

Neurology: Alzheimer's Disease Research Center (ADRC) | Clinical Neurosciences Imaging Center | Memory Disorders & Cognitive Neurology

Faculty Research

Yale Medicine

Biography

Dr. Salardini finished his medical degree in 1999 from University of New South Wales (UNSW) in Sydney, Australia. He combined his undergraduate medical degree (MBBS) with a degree in science majoring in anatomy and physiology to take advantage of the prestigious advanced science anatomy program in UNSW. During this Dr Salardini developed an interest in cognition specially through the comparative study of brain anatomy across species. His teachers included the paleontologist Mike Archer (later director of the Australian Museum) specializing in marsupials and the comparative neuroanatomist Kenneth Ashwell. His research project involved the mapping of raphe nuclei in Tammar Wallaby. During his medical training the example of one of his professors, James W Lance, a leader in Australian neurology, prompted him to choose neurology over the two sister disciplines of neurosurgery and psychiatry. Upon graduation, he did his preliminary training in internal medicine with the Royal Australasian College of Physicians. He briefly worked as a critical care medical officer to save up money for further education in the US. In 2007 he embarked on a two year clinical postdoctoral fellowship in movement disorder at Yale working for Professor B Jabbari. He then completed a residency in University of Florida where he was mentored by the great Cognitive Neurologist Kenneth Heilman. Upon graduation he came to Yale to complete a two year fellowship in Behavioral Neurology and Neuropsychiatry under the mentorship of Dr S Strittmatter, one of this country's leading research neurologists. He is now the associate leader of the clinical core of Alzheimer Disease Research Center at Yale and his research interest include amyloid and microglial brain imaging in Alzheimer's. Dr Salardini is the author of several peer reviewed papers and book chapters and is the editor of The Hospital Neurology Book a new textbook by McGraw-Hill to be released in 2016. He co-directs the memory clinic and sees patients with memory, language and cognition problems due to neurodegenerative and other neurological causes. Articles about his work have appeared on National Public Radio, CT Post, washingtonpost.com, Usnews.com, New York Post, Daily Mail (UK), Mirror (UK), Times of London, ITV News (UK), BBC World Service (UK) and BBC radio Scotland.


Education & Training

MD University of New South Wales (1999)
BSc University of New South Wales, Anatomy/Physiology (1994)
Fellowship Yale University School of Medicine
Residency University of Florida
Postdoctoral Fellowship Yale School of Medicine
Internal Medicine Registrar Royal Australasian College of Physicians

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Contact Info

Arash Salardini, MD
Patient Care Locations
Yale NeurologyYale New Haven Hospital
20 York Street

New Haven, CT 06510
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Yale NeurologyYale Physicians Building
800 Howard Avenue

New Haven, CT 06519
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Mailing Address
PO Box 208018
New Haven, CT 06520-8018
Examples of imaging from our patients

A shows reduction in dopamine innervation in the basal ganglia of a patient with Lewy Body Disease. B shows a negative amyloid scan with Florbetapir where most of the binding is non-specifically to the white matter. C shows specific amyloid binding in the cortex. D shows an FDG PET which shows temporoparietal hypometabolism consistent with AD. Compare with the normal uptake in F. The corresponding MRI in G shows shrinkage in the area of brain responsible for memories.. E shows asymmetrical reduction in the frontal and parietal cortices consistent with frontotemporal dementia. The corresponding MRI image shows asymmetrical atrophy of temporal pole and the “knife edge” sign. I shows preferential atrophy of parietal lobe and widening of the posterior cortical sulci consistent with early posterior cortical atrophy which is a type of Alzheimer's disease.

The Hospital Neurology Book

A new textbook to be published in 2016, approaches the diagnosis and treatment of neurological disease from a practical and epidemiologically appropriate perspective. It also deals with common medical problems faced by neurology inpatients.